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Polycystic Ovarian Syndrome, PCOS

What is Polycystic Ovarian Syndrome?

PCOS, short for polycystic ovarian syndrome, is a common cause of anovulation and female infertility
It is also sometimes referred to as PCO (polycystic ovaries) or PCOD (polycystic ovarian disease).
Women with polycystic ovaries and fertility problems:
Do not release an egg (ovulate) regularly
Have ovaries that contain many small cystic structures, about 2-9 mm in diameter

How does normal ovulation work?

In a normal menstrual cycle with ovulation, a mature follicle - which is also a cystic structure - develops. The size of a mature follicle that is ready to ovulate is about 18 to 28mm in diameter.

About 14 days after ovulation the woman would be expected to get a period if she is not pregnant
The basic difference between polycystic and normal ovaries is that although the polycystic ovaries contain many small antral follicles with eggs in them, the follicles do not develop and mature properly - so there is no ovulation.
Since women with polycystic ovaries do not ovulate regularly, they do not get regular menstrual periods
Symptoms of polycystic ovarian syndrome
A common scenario in women with polycystic ovaries is:

Irregular menstrual cycles, called oligomenorrhea, and sometimes a total lack of periods, referred to by doctors as amenorrhea
Gradually worsening of the excess hair growth over the years
Women with polycystic ovaries often have an excess amount of the male hormones testosterone and androstenedione - resulting in high testosterone levels in the blood. Women with PCO and high testosterone can have increased facial and body hair growth - called hirsutism.

What are the chances of having PCOS?

It is estimated that polycystic ovarian syndrome affects about 8-10% of women of reproductive age. It is very common.

What is the infertility rate with PCOS?

The infertility rate with polycystic ovaries is very high. these women usually will have difficulty getting pregnant - and usually require treatment to improve chances for pregnancy.
Some women with polycystic ovary syndrome will ovulate (release a mature egg) occasionally - others do not ever ovulate. In order to conceive, sperm must find and fertilize a mature egg - so we need to ovulate.

Can I conceive with PCOS?

The good news is that the chance of getting pregnant with polycystic ovarian syndrome using fertility treatments is very good. The great majority of women with polycystic ovarian syndrome will be able to have a baby with fertility treatment.
For young women under age 35 with polycystic ovaries, the real question is more about whichtreatment will be effective - and not so much whether any treatment can ever work.
As far as the chances for pregnancy with PCOS - pregnancy statistics are difficult to give without knowing the details of the individual case.

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